“SIEUR” is a valid word. — 5 points Scrabble

surehaving or feeling no doubt or uncertainty; confident and assured
risea growth in strength or number or importance
sirea title of address formerly used for a man of rank and authority
usera person who makes use of a thing; someone who uses or employs something
rusea deceptive maneuver (especially to avoid capture)
reisany rational or irrational number
suera man who courts a woman
ruesEuropean strong-scented perennial herb with grey-green bitter-tasting leaves; an irritant similar to poison ivy
iresa strong emotion; a feeling that is oriented toward some real or supposed grievance

sirterm of address for a man
usethe act of using
sueFrench writer whose novels described the sordid side of city life (1804-1857)
rueEuropean strong-scented perennial herb with grey-green bitter-tasting leaves; an irritant similar to poison ivy
sri
ser
rei
resa widely distributed system consisting of all the cells able to ingest bacteria or colloidal particles etc, except for certain white blood cells
sei
irea strong emotion; a feeling that is oriented toward some real or supposed grievance
ers

ishave the quality of being; (copula, used with an adjective or a predicate noun)
usNorth American republic containing 50 states - 48 conterminous states in North America plus Alaska in northwest North America and the Hawaiian Islands in the Pacific Ocean; achieved independence in 1776
era trivalent metallic element of the rare earth group; occurs with yttrium
rea rare heavy polyvalent metallic element that resembles manganese chemically and is used in some alloys; is obtained as a by-product in refining molybdenum
sia tetravalent nonmetallic element; next to oxygen it is the most abundant element in the earth's crust; occurs in clay and feldspar and granite and quartz and sand; used as a semiconductor in transistors
esa radioactive transuranic element produced by bombarding plutonium with neutrons

SIEUR