“PEMPHIX” is a valid word. — 23 points Scrabble

pipea tube with a small bowl at one end; used for smoking tobacco
pimpsomeone who procures customers for whores (in England they call a pimp a ponce)
hempa plant fiber

him
piedish baked in pastry-lined pan often with a pastry top
mixa commercially prepared mixture of dry ingredients
hipeither side of the body below the waist and above the thigh
pepliveliness and energy
pipa disease of poultry
hemthe edge of a piece of cloth; especially the finished edge that has been doubled under and stitched down
phithe 21st letter of the Greek alphabet
hexan evil spell
hepinformed about the latest trends
imp(folklore) fairies that are somewhat mischievous
pixa chest in which coins from the mint are held to await assay
hiemove fast
peh

mea state in New England
hea very light colorless element that is one of the six inert gasses; the most difficult gas to liquefy; occurs in economically extractable amounts in certain natural gases (as those found in Texas and Kansas)
hian expression of greeting
ema quad with a square body
eh
hma metric unit of length equal to 100 meters
exa man who was formerly a certain woman's husband
midestruction of heart tissue resulting from obstruction of the blood supply to the heart muscle
pithe ratio of the circumference to the diameter of a circle; approximately equal to 3.14159265358979323846...
xithe cardinal number that is the sum of ten and one
pethe 17th letter of the Hebrew alphabet

PEMPHIX